SYNTHESIS AND BIOTECHNOLOGICAL STUDY OF ETHYL 2-((E)-2-((E) PHENYLALLYLIDENE) HYDRAZINECARBOTHIOAMIDO)ACETATE
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Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
CEP USM
Abstract
The quality and length of human life is directly related to the development of medicine, in
particular drugs. The modern world is constantly in the process of developing new, more effective
drugs. Thiosemicarbazones may be one of the promising solutions. Despite their outstanding
biological activities, many of them are toxic and cannot be used as medicines. The solution may
be thiosemicarbazones, which are based on natural substances. This is expected to signifcantly
reduce toxicity without impairing the biological activity of the substances. In this regard, for this
work, a thiosemicarbazone was synthesized, which is based on two natural substances, glycine
and cinnamaldehyde. To test the toxicity of this substance, some strains of cyanobacteria were
used in this article. In addition to the lack of toxicity to these microorganisms, the synthesized
thiosemicarbazone had a biostimulating effect.
Description
CIURSIN, Andrei, TROFIM, Alina, RUSNAC, Roman. Synthesis and biotechnological study of ethyl 2-((e)-2-((e) phenylallylidene) hydrazinecarbothioamido)acetate. In: Integrare prin cercetare și inovare: conferința științifică națională cu participare internațională. Ştiinţe ale naturii și exacte, 9-10 noiembrie 2023. CEP USM, 2024, pp. 473-482. ISBN 978-9975-62-690-3.
Keywords
thiosemicarbazone, cyanobacteria cultivation, non-toxic, cinnamaldehyde
Citation
CIURSIN, Andrei, TROFIM, Alina, RUSNAC, Roman. Synthesis and biotechnological study of ethyl 2-((e)-2-((e) phenylallylidene) hydrazinecarbothioamido)acetate. In: Integrare prin cercetare și inovare: conferința științifică națională cu participare internațională. Ştiinţe ale naturii și exacte, 9-10 noiembrie 2023. CEP USM, 2024, pp. 473-482. ISBN 978-9975-62-690-3.