Synthesis, Structure, and Biological Activity of Copper(II), Nickel(II), Cobalt(III), and Iron(III) Coordination Compounds with 2-{2-[(Prop-2-en-1-yl)carbamothioyl]hydrazinylidene}propanoic Acid [Articol]
dc.contributor.author | Gulea, Aurelian | |
dc.contributor.author | Graur, Vasilii | |
dc.contributor.author | Diurici, E. | |
dc.contributor.author | Ulchina, Ianina | |
dc.contributor.author | Bouroș, Pavlina | |
dc.contributor.author | Balan, Greta | |
dc.contributor.author | Burduniuc, Olga | |
dc.contributor.author | Țapcov, Victor | |
dc.contributor.author | Rudic, Valeriu | |
dc.date.accessioned | 2023-10-27T09:22:10Z | |
dc.date.available | 2023-10-27T09:22:10Z | |
dc.date.issued | 2020 | |
dc.description.abstract | 2-Oxopropanoic acid reacts in ethanol with N-(prop-2-en-1-yl)hydrazinecarbothioamide in a 1 : 1 mole ratio to form thiosemicarbazone H2L. Coordination compounds Cu(HL)X [X = Cl–, Br–, NO3–], Cu(H2O)(L), Ni(HL)2, Co(HL)2X [X = Cl–, Br–], and Fe(HL)2X [X = NO3–, Br–] are formed in the reactions of H2L with copper(II), nickel(II), cobalt(II), and iron(III) salts. The reactions of Cu(H2O)(L) with imidazole (Im) and 3,4-dimethylpyridine (3,4-Lut) result in mixed-ligand complexes Cu(A)(L) [A = Im, 3,4-Lut]. The structures of two copper complexes were determined by single crystal X-ray diffraction analysis. The synthesized complexes exhibit selective antimicrobial and antifungal activity in the concentration range of 15.62–1000 μg/mL. The introduction of amines into the inner sphere of copper complexes leads to an increase in the antimicrobial activity. | en |
dc.description.sponsorship | The work was carried out within the framework of the State program of the Republic of Moldova (project 20.80009.5007.10). | en |
dc.identifier.citation | GULEA, Aurelian, GRAUR, Vasilii , DIURICI, E., ULCHINA, Ianina, BOUROȘ, Pavlina, BALAN, Greta, BURDUNIUC , Olga, ȚAPCOV, Victor , RUDIC, Valeriu. Synthesis, Structure, and Biological Activity of Copper(II), Nickel(II), Cobalt(III), and Iron(III) Coordination Compounds with 2-{2-[(Prop-2-en-1-yl)carbamothioyl]hydrazinylidene}propanoic Acid. În: Russian Journal of General Chemistry, 2020, vol. 90, pp. 2120-2127. ISSN 1070-3632 | en |
dc.identifier.issn | 1070-3632 | |
dc.identifier.uri | https://msuir.usm.md/handle/123456789/11486 | |
dc.identifier.uri | https://doi.org/10.1134/S107036322011016X | |
dc.language.iso | en | en |
dc.subject | coordination compounds | en |
dc.subject | pyruvic acid 4-allylthiosemicarbazone | en |
dc.subject | antimicrobial activity | en |
dc.subject | antifungal activity | en |
dc.title | Synthesis, Structure, and Biological Activity of Copper(II), Nickel(II), Cobalt(III), and Iron(III) Coordination Compounds with 2-{2-[(Prop-2-en-1-yl)carbamothioyl]hydrazinylidene}propanoic Acid [Articol] | en |
dc.type | Article | en |