Synthesis, Structure, and Biological Activity of Copper(II), Nickel(II), Cobalt(III), and Iron(III) Coordination Compounds with 2-{2-[(Prop-2-en-1-yl)carbamothioyl]hydrazinylidene}propanoic Acid [Articol]

dc.contributor.authorGulea, Aurelian
dc.contributor.authorGraur, Vasilii
dc.contributor.authorDiurici, E.
dc.contributor.authorUlchina, Ianina
dc.contributor.authorBouroș, Pavlina
dc.contributor.authorBalan, Greta
dc.contributor.authorBurduniuc, Olga
dc.contributor.authorȚapcov, Victor
dc.contributor.authorRudic, Valeriu
dc.date.accessioned2023-10-27T09:22:10Z
dc.date.available2023-10-27T09:22:10Z
dc.date.issued2020
dc.description.abstract2-Oxopropanoic acid reacts in ethanol with N-(prop-2-en-1-yl)hydrazinecarbothioamide in a 1 : 1 mole ratio to form thiosemicarbazone H2L. Coordination compounds Cu(HL)X [X = Cl–, Br–, NO3–], Cu(H2O)(L), Ni(HL)2, Co(HL)2X [X = Cl–, Br–], and Fe(HL)2X [X = NO3–, Br–] are formed in the reactions of H2L with copper(II), nickel(II), cobalt(II), and iron(III) salts. The reactions of Cu(H2O)(L) with imidazole (Im) and 3,4-dimethylpyridine (3,4-Lut) result in mixed-ligand complexes Cu(A)(L) [A = Im, 3,4-Lut]. The structures of two copper complexes were determined by single crystal X-ray diffraction analysis. The synthesized complexes exhibit selective antimicrobial and antifungal activity in the concentration range of 15.62–1000 μg/mL. The introduction of amines into the inner sphere of copper complexes leads to an increase in the antimicrobial activity.en
dc.description.sponsorshipThe work was carried out within the framework of the State program of the Republic of Moldova (project 20.80009.5007.10).en
dc.identifier.citationGULEA, Aurelian, GRAUR, Vasilii , DIURICI, E., ULCHINA, Ianina, BOUROȘ, Pavlina, BALAN, Greta, BURDUNIUC , Olga, ȚAPCOV, Victor , RUDIC, Valeriu. Synthesis, Structure, and Biological Activity of Copper(II), Nickel(II), Cobalt(III), and Iron(III) Coordination Compounds with 2-{2-[(Prop-2-en-1-yl)carbamothioyl]hydrazinylidene}propanoic Acid. În: Russian Journal of General Chemistry, 2020, vol. 90, pp. 2120-2127. ISSN 1070-3632en
dc.identifier.issn1070-3632
dc.identifier.urihttps://msuir.usm.md/handle/123456789/11486
dc.identifier.urihttps://doi.org/10.1134/S107036322011016X
dc.language.isoenen
dc.subjectcoordination compoundsen
dc.subjectpyruvic acid 4-allylthiosemicarbazoneen
dc.subjectantimicrobial activityen
dc.subjectantifungal activityen
dc.titleSynthesis, Structure, and Biological Activity of Copper(II), Nickel(II), Cobalt(III), and Iron(III) Coordination Compounds with 2-{2-[(Prop-2-en-1-yl)carbamothioyl]hydrazinylidene}propanoic Acid [Articol]en
dc.typeArticleen

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