USE OF MICROMOLECULAR COPPER COMPLEXES OF THIOSEMICARBAZIDES AS AN ENDOGENOUS CATALASE INDUCER/ACTIVATOR

Abstract

Oxidative stress is a major mechanism in the pathogenesis of many diseases, including severe multifactorial ones. Catalase (CAT), along with superoxide dismutase, is one of the first-line antioxidant defense enzymes. The development of methods/compounds that can increase/induce CAT will provide new possibilities to strengthen antioxidant protection and prevent oxidative damage to cells and tissues.Oxidative stress is a major mechanism in the pathogenesis of many diseases, including severe multifactorial ones. Catalase (CAT), along with superoxide dismutase, is one of the first-line antioxidant defense enzymes. The development of methods/compounds that can increase/induce CAT will provide new possibilities to strengthen antioxidant protection and prevent oxidative damage to cells and tissues.