Sinteza compuşilor biologic activi pe baza nitrofurantoinei [Articol]

Abstract

The present work is dedicated to methods of synthesis of new substances with potential biological activity, what could be used as drugs for different diseases, also for establish relation between structure of substances and biological activity. Furane derivatives are well known as pharmaceutical preparation, in special the derivatives of 5-nitro-2-furaldehide, which are characterized by a large spectrum of antimicrobial activity. At the same time, drugs based of furan has low toxicity, they are stable and are obtained by relative simple method from different easy accessible raw material.