EFECTUL ANTIBACTERIAN ŞI ANTIFUNGIC AL UNOR COMPUŞI NOI

Simple item page
dc.contributor.authorŢapcov, Victor
dc.contributor.authorGulea, Aurelian
dc.contributor.authorPrisacari, Viorel
dc.contributor.authorBurlacov, Svetlana
dc.date.accessioned2019-11-04T10:17:25Z
dc.date.available2019-11-04T10:17:25Z
dc.date.issued2010
dc.description.abstractPentru o preformulare şi formulare corectă a medicamentelor este necesar să cunoaştem datele structural-moleculare ale substanţelor medicamentoase: masa moleculară; aria suprafeţei polare; numărul total al legăturilor de rotaţie; suma donorilor şi acceptorilor de protoni. La fel este important şi cunoaşterea parametrilor biofarmaceutici: capacitatea de partiţie a formelor neionizate (LogP); capacitatea de distribuţie la diferite valori ale pH (LogD); solubilitatea (LogS) şi constanta de ionizare (pKa).en
dc.description.abstractFor correct formulation of the drugs, the structural-molecular properties of the substances, such as mo- lecular weight, polar surface area, total number of the rotate bound, total number of the donor and acceptor of protons are needed to be known. As well the biopharmaceutical parameters: partition coeffi cient octanol/water (LogP); distribution coeffi cient (LogD); solubility (LogS) and ionization constant (pKa) which are also very important.
dc.identifier.citationŢAPCOV, V., GULEA, A. et al. Efectul antibacterian şi antifungic al unor compuşi noi. In: Buletinul Academiei de Ştiinţe a Moldovei. Ştiinţe Medicale. 2010, nr. 1(24), pp. 43-50. ISSN 1857-0011.en
dc.identifier.issn1857-0011
dc.identifier.urihttps://msuir.usm.md/handle/123456789/2262
dc.language.isoroen
dc.subjecttehnologia medicamenteloren
dc.subjectfarmaceuticaen
dc.subjectchimia anorganicaen
dc.subjectpreparatelor antibacterieneen
dc.titleEFECTUL ANTIBACTERIAN ŞI ANTIFUNGIC AL UNOR COMPUŞI NOIen
dc.typeArticleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Efectul antibacterial si antifungic al unor compusi noi.pdf
Size:
307.72 KB
Format:
Adobe Portable Document Format
Description:
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

2. Articole