SUBSTITUTED 1,3-PHENYL(PYRIDYL) PROPENONES AND DERIVATIVES WITH THIOSEMICARBAZIDIC GROUPS. STRUCTRURE – (HL-60) ANTILEUKEMIA ACTIVITY RELATIONSHIP

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dc.contributor.authorPopușoi, Ana
dc.contributor.authorBarba, Nicanor
dc.contributor.authorGulea, Aurelian
dc.contributor.authorRoy, Jenny
dc.contributor.authorPoirier, Donald
dc.date.accessioned2023-10-19T12:49:55Z
dc.date.available2023-10-19T12:49:55Z
dc.date.issued2014
dc.description.abstract3-(4-(Dimethylamino)phenyl-1-(4-isothiocyanatophenyl)prop-2-en-1-one was obtained from the corresponding N,N-dimethylthyoureas by elimination of dimethylamine at heating with gaseous hydrogen chloride in chloroform and 1-(4-isothiocyanatophenyl)-3-(pyridin-2-il)prop-2-en-1-one by treating 1,1-dimethyl-3-(4-(3-(pyridin-2-il)-acryloyl)-phenyl)thyourea with acetic anhydride. For all obtained compounds in the course of reaction the antileukemia activity was investigated.en
dc.identifier.citationPOPUȘOI, Ana, GULEA, Aurelian, BARBA, Nicanor, ROY, Jenny, POIRIER, Donald. Substituted 1,3-phenyl (pyridyl) propenones and derivatives with thiosemicarbazidic groups. Structrure – (hl-60) antileukemia activity relationship. În: Chemistry Journal of Moldova, 2014, nr. 2(9), pp. 67-73. ISSN 1857-1727en
dc.identifier.issn1857-1727
dc.identifier.urihttps://msuir.usm.md/handle/123456789/11395
dc.identifier.urihttp://10.19261/cjm.2014.09(2).10
dc.language.isoenen
dc.subjectchalconesen
dc.subjectisothiocyanatopropenonesen
dc.subjectthioureasen
dc.subjectantileukemia activityen
dc.titleSUBSTITUTED 1,3-PHENYL(PYRIDYL) PROPENONES AND DERIVATIVES WITH THIOSEMICARBAZIDIC GROUPS. STRUCTRURE – (HL-60) ANTILEUKEMIA ACTIVITY RELATIONSHIPen
dc.typeArticleen

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