Studii RMN ale 1-(2-oxopropil)spiro[[1,3]indolin-3,2’- [1,3]dioxolan-2-onei cu proprietăţi anxiotice [Articol]
| dc.contributor.author | Gorincioi, Elena | ro |
| dc.contributor.author | Ștefaneţ, Tatiana | ro |
| dc.contributor.author | Stîngaci, Eugenia | ro |
| dc.contributor.author | Valica, Vladimir | ro |
| dc.contributor.author | Macaev, Fliur | ro |
| dc.date.accessioned | 2026-01-29T10:28:53Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | The current communication reports on the use of Nuclear Magnetic Resonance (NMR) Spectroscopy for the NMR characterization of 1-(2-oxopropyl)spiro[[1,3]indoline-3,2’- [1,3]dioxolan-2-one, for which anxyolitic and antidepressant effects have been found in preliminary tests. The combination of 1D and 2D homo- and heterocorrelation 1H/13C NMR experiments provided the unambiguous set of assignments. Studies regarding the properties of the title compound and its congeners are of great interest, as these compounds may be advanced for further biological testing and preclinical development, or used as possible lead compounds for the future design of Monoamine oxidase inhibitors. | en |
| dc.description.provenance | Submitted by Ludmila Vedrascu (ludmila_vedrascu@yahoo.com) on 2026-01-29T10:28:53Z No. of bitstreams: 1 88_GORINCIOI Elena.pdf: 879595 bytes, checksum: 8b0ccb1416ce023f27058080d8892893 (MD5) | en |
| dc.description.provenance | Made available in DSpace on 2026-01-29T10:28:53Z (GMT). No. of bitstreams: 1 88_GORINCIOI Elena.pdf: 879595 bytes, checksum: 8b0ccb1416ce023f27058080d8892893 (MD5) Previous issue date: 2025 | en |
| dc.description.sponsorship | Cercetarea a fost susținută de subprogramele 010601 și 080301 finanțate de Ministerul Educației și Cercetării al Republicii Moldova. | ro |
| dc.identifier.citation | GORINCIOI, Elena; ȘTEFANEȚ, Tatiana; STÎNGACI, Eugenia; VALICA, Vladimir şi Fliur MACAEV. Studii RMN ale 1-(2-oxopropil)spiro[[1,3]indolin-3,2’- [1,3]dioxolan-2-onei cu proprietăţi anxiotice. In: Integrare prin cercetare şi inovare: conferinţa ştiinţifică naţională cu participare internaţională. Ştiinţe Exacte și ale naturii. Chișinău, 6-7 noiembrie 2025. Chișinău: CEP USM, 2025, pp. 677-684. ISBN 978-9975-62-989-8 (PDF). Disponibil: https://doi.org/10.59295/spd2025e.88 | ro |
| dc.identifier.isbn | 978-9975-62-989-8 (PDF) | |
| dc.identifier.uri | https://doi.org/10.59295/spd2025e.88 | |
| dc.identifier.uri | https://msuir.usm.md/handle/123456789/19948 | |
| dc.language.iso | ro | ro |
| dc.publisher | Universitatea de Stat din Moldova | ro |
| dc.subject | antidepressant | ro |
| dc.subject | anxyoliotic | ro |
| dc.subject | isatine derivatives | ro |
| dc.subject | NMR | ro |
| dc.title | Studii RMN ale 1-(2-oxopropil)spiro[[1,3]indolin-3,2’- [1,3]dioxolan-2-onei cu proprietăţi anxiotice [Articol] | ro |
| dc.title.alternative | NMR STUDIES OF 1-(2-OXOPROPYL)SPIRO[[1,3]INDOLINE-3,2’-[1,3] DIOXOLAN-2-ONE WITH ANXIOLYTIC PROPERTIES | en |
| dc.type | Article |