Potenţialul profilactic şi terapeutic al resveratrolului în reducerea cetonuriei şi proteinuriei induse de diabetul experimental [Articol]

Abstract

Ketonuria and proteinuria are important markers of metabolic imbalances and kidney damage in the context of diabetes mellitus. The present study investigated the therapeutic effect of resveratrol, a natural polyphenolic compound with antioxidant and anti-inflammatory properties, on ketonuria and proteinuria levels in experimentally induced diabetes in white laboratory rats. Its administration led to a reduction in urinary excretion of ketones and proteins, suggesting a protective effect on renal tissue and a possible alleviation of oxidative stress and diabetes-associated inflammation. The obtained results support the need for further research to elucidate the underlying molecular mechanisms and evaluate the applicability of this bioactive compound.