Stresul oxidativ în displazia bronhopulmonară la copiii născuți premature
| dc.contributor.author | Ceahlău, Mariana | ro |
| dc.contributor.author | Selevestru, Rodica | ro |
| dc.contributor.author | Șciuca, Svetlana | ro |
| dc.date.accessioned | 2025-01-28T07:25:52Z | |
| dc.date.issued | 2024 | |
| dc.description.abstract | Bronchopulmonary dysplasia begins in the neonatal period and is responsible for recurrent respiratory morbidity, chronic bronchopulmonary diseases of the child. The purpose of the research - evaluation of biochemical markers of oxidative stress in children with bronchopulmonary dysplasia (BPD). A cohort study was conducted that included 41 children with a history of preterm birth and postnatal oxygen therapy in respiratory distress who achieved BPD. The comparative study with preterm infants who did not perform BPD (40 infants) identified a 4.86-fold (p<0.001) increase in total pro-oxidant activity and a significant 62% (p<0.001) increase in malondialdehyde content in children. With BPD, but also a 12% (p<0.001) reduction in nitric oxide. Children with bronchopulmonary dysplasia show disorders of the redox status by triggering oxidative/nitrosative stress, which are included in the pathogenic mechanisms of chronic bronchopulmonary processes in children born prematurely. | en |
| dc.description.provenance | Submitted by faureanu tanea (erika.bcu@gmail.com) on 2025-01-28T07:25:52Z No. of bitstreams: 1 16_Ceahlău Mariana.pdf: 414964 bytes, checksum: 998f5b4ee9f7fc67b904075588b07f4f (MD5) | en |
| dc.description.provenance | Made available in DSpace on 2025-01-28T07:25:52Z (GMT). No. of bitstreams: 1 16_Ceahlău Mariana.pdf: 414964 bytes, checksum: 998f5b4ee9f7fc67b904075588b07f4f (MD5) Previous issue date: 2024 | en |
| dc.identifier.citation | CEAHLĂU, Mariana; Olga TAGADIUC; Rodica SELEVESTRU și Svetlana ȘCIUCA. Stresul oxidativ în displazia bronhopulmonară la copiii născuți premature. In: Fiziologia şi sănătatea: materialele congresului VIII al fiziologilor din Republica Moldova cu participare internaţională, 14-15 noiembrie 2024. Chişinău: Editura USM, 2024, pp. 154-161. ISBN 978-9975-62-815-0; ISBN 978-9975-62-816-7 (PDF). | ro |
| dc.identifier.doi | https://doi.org/10.52692/cfzl2024.16 | |
| dc.identifier.isbn | ISBN 978-9975-62-815-0 | |
| dc.identifier.isbn | ISBN 978-9975-62-816-7 (PDF) | |
| dc.identifier.uri | https://msuir.usm.md/handle/123456789/16552 | |
| dc.identifier.uri | https://doi.org/10.52692/cfzl2024.16 | |
| dc.language.iso | ro | |
| dc.publisher | Editura USM | |
| dc.subject | oxidative stress | en |
| dc.subject | bronchopulmonary dysplasia | en |
| dc.subject | children | en |
| dc.title | Stresul oxidativ în displazia bronhopulmonară la copiii născuți premature | ro |
| dc.type | Article |