MECANISMUL DE PROTEOLIZĂ A FICOCIANINEI, PROTEINEI BIOACTIVE DIN SPIRULINĂ SUB ACŢIUNEA PAPAINEI
Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
CEP USM
Abstract
Elaborarea unor procedee de obţinere a peptidelor bioactive din ficocianină prin intermediul hidrolizei proteolitice
prezintă un interes sporit pentru cercetători în contextul utilizării acestora în calitate de remedii anticancer şi pentru alte
proprietăţi terapeutice. Peptidele derivate din ficocianină ar putea manifesta proprietăţi terapeutice mult mai pronunţate
comparativ cu ficocianina. În prezenta lucrare sunt studiate dinamica proteolizei ficocianinei cu papaina şi mecanismul
de hidroliză a acestei proteine
The elaboration of the procedures of obtaining of bioact ive peptides derived from phycocyanin, as a result of it proteolytic hydrolysis presents great interest for researchers in the terms of theirs use as anti-cancer drugs and for other therapeutic properties. It can be assumed that peptides derived from phycocyanin could manifest more pronounced therapeutic effects compared to phycocyanin. Dynamics of phycocyanin proteolisis by papain, as well as mechanism of phycocyanin hydrolysis were st udied in the present work.
The elaboration of the procedures of obtaining of bioact ive peptides derived from phycocyanin, as a result of it proteolytic hydrolysis presents great interest for researchers in the terms of theirs use as anti-cancer drugs and for other therapeutic properties. It can be assumed that peptides derived from phycocyanin could manifest more pronounced therapeutic effects compared to phycocyanin. Dynamics of phycocyanin proteolisis by papain, as well as mechanism of phycocyanin hydrolysis were st udied in the present work.
Description
Keywords
Spirulina, C-ficocianina, proteoliză, peptide bioactive
Citation
RUDAKOVA, Angela, SHUTOV, Andrei, RUDACOV, Serghei, BULIMAGA, Valentina, CLIMOVA, Natalia, KAHOVSKAIA, Irina, PISOVA; Maria. Mecanismul de proteoliză a ficocianinei, proteinei bioactive din Spirulină sub acţiunea papainei . In: Studia Universitatis Moldaviae. Seria Ştiinţe reale şi ale naturii. Biologie. Chimie. Revistă ştiinţifică. 2015, nr. 6(86), pp. 15-20