ROLUL MICROBIOTEI INTESTINALE ÎN MENȚINEREA STĂRII IMUNOMETABOLICE ȘI PREVENIREA METAINFLAMAȚIEI

Abstract

The results of scientific research indicate that an important role in the pathogenesis of obe sity and the metabolic syndrome is played by the intestinal microbiota (MI), which is involved in the regulation of the host’s metabolism through symbiotic interactions with it. At the same time, a shift in the gut’s microbial ecosystem, according to cutting-edge research, contributes to signi ficant metabolic and immune disturbances in animals and humans. The environment and diet in the first 3 years of life are essential for the acquisition of an adult type of microbiota and the for mation of a microbiota-host symbiosis, which significantly affects the development of the immune and nervous systems. Although the microbiota is very diverse in the intestines, for example, there are representatives of about 70 types of bacteria, however, most of them are represented by two types: Bacteroidetes and Firmicutes.