Facultatea de Biologie și Geoştiinţe / Faculty of Biology and Geosciences

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    NOI PREMIXURI FURAJERE ÎN BAZA BIOMASEI DE SPIRULINĂ CU SELEN
    (CEP USM, 2014) Rudic, Valeriu; Djur, Svetlana; Cepoi, Liliana; Chiriac, Tatiana; Rudi, Ludmila; Codreanu, Svetlana; Ghelbet, Viorica
    There have been proposed the recipesfor preparing two feed premixes with organic selenium according to the sourceofinorganicseleniumused: “Spirulina with organic selenium 1 and 2” and “protein feed premix with organic selenium 1 and2”. The proposedpremixescomprise amulticomponent synergisticcombination in case of the first technological recipe and Spirulina extract containing freea mino acids, oligopeptides and selenium-containing proteinsin case of the second recipe exhibiting significant anti-oxidantactivity andimmunomodulatory effect.
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    EFICIENŢA TRATAMENTULUI DEGENERESCEŢEI MACULARE LEGATE DE VÂRSTĂ LA ADMINISTRAREA PREPARATULUI BIOR
    (CEP USM, 2014) Rudic, Valeriu; Cuşnir, V.; Andronic, Serghei; Dumbrăveanu, Lilia; Cuşnir, Vitalie
    Age related macular degeneration is an increasing problem in ophthalmology. Current treatment options can delay progression and continue researches can discover new ways to halt and reverse the degenerative processes of the retina. The study included 62 patients (124 affected eyes) affected by ARMD, surveyed and treated in the Ophthalmology Clinic Nr.2 of SUMPh “Nicolae Testemitanu”. The 32 patients (64 affected eyes) from the basic lot were treated by parabulbar injection of BioR 0,5%: from 10 day. Effectuating this study we established that the use of BioR 0,5% in the treatment of ARMD is effective, comparatively with the traditional treatment.
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    STUDIUL ACUMULĂRII CUPRULUI LA CULTIVAREA CIANOBACTERIEI SPIRULINA PLATENSIS ÎN PREZENŢA COMPUŞILOR COORDINATIVI AI Cu(II)
    (CEP USM, 2009) Rudic, Valeriu; Batîr, Ludmila; Bulimaga, Valentina; Zosim, Liliana; Elenciuc, Daniela; Gulea, Aurelian; Ţapcov, Victor
    The acumulation of copper in biomass of cyanobacteria Spirulina platensis CNM - CB – 02 at the cultivation in the presence of coordination compounds of Cu (II) has been determined. Bioaccumulation of copper depends on the nature of ligands of the compounds. It was established that compounds [CuL2(Sfz)3H2O] and [Cu(L-2H)] contribute to the increasing of copper content in the biomass of spirulina in 2,94 – 3,42 times compared to the reference sample.
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    MODIFICAREA COMPONENŢEI CALITATIVE A PROTEINELOR LA CIANOBACTERIA SPIRULINA PLATENSIS CULTIVATĂ ÎN PREZENŢA UNOR COMPUŞI COORDINATIVI AI CR(III)
    (CEP USM, 2008) Rudic, Valeriu; Bulimaga, Valentina; Ciumac, Daniela; Zosim, Liliana; Chiriac, Tatiana; Efremova, Nadejda
    SDS-electrophoresis of polypeptide chains of total protein fraction obtained from Spirulina cultivated in the presence of Cr(III) coordination compounds have been carried out. New bands with apparent molecular mass 60, 4 kDa and 66, 7 kDa have been detected in the presence of Cr(III) coordination compounds.
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    TEHNOLOGIA OBŢINERII ÎN BAZA BIOMASEI DE SPIRULINĂ A REMEDIULUI MEDICAMENTOS FERRIBIOR ŞI STUDIUL ACŢIUNII LUI ANTIANEMICE
    (CEP USM, 2008) Rudic, Valeriu; Gudumac, Valentin; Zosim, Liliana; Chiriac, Tatiana; Bulimaga, Valentina; Ciumac, Daniela
    The technological scheme of obtaining of the preparation Ferribior with high content of organic iron (0,04-0,05%)and other bioactive substances: immunoactive amino acids (71% from free total amino acids and 70,57% from conjugated amino acids) and polysaccharides (6-7%) from spirulina biomass has been elaborated. The capacity of Ferribior to reestablish the plasmatic iron and zinc level and to stimulate hemathopoesis at experimental rats has been demonstrated.
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    COMPONENŢA AMINOACIDĂ A OLIGOPEPTIDELOR ŞI AMINOACIZILOR LIBERI DIN BIOMASA DE SPIRULINĂ CULTIVATĂ ÎN PREZENŢA UNOR COMPUŞI COORDINATIVI AI Fe(III) Ş I Zn(II)
    (CEP USM, 2007) Rudic, Valeriu; Chiriac, Tatiana; Bulimaga, Valentina; Zosim, Liliana; Turtă, Constantin; Prodius, Denis
    Amino acid composition of oligopeptids and amino acids fractions in spirulina biomass cultivated in the presence of some coordinative compounds of Fe(III) and Zn(II) has been determined. High content of essential and especially immunoactive amino acids was pointed out in this study.
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    EFECTUL STIMULATOR AL COMPUŞILOR COORDINATIVI AI CROMULUI(III) ASUPRA PRODUCTIVITĂŢII SPIRULINEI
    (CEP USM, 2007) Rudic, Valeriu; Gulea, Aurelian; Bulimaga, Valentina; Ciumac, Daniela; Ciornea, Valeriu; Zosim, Liliana; Popa, Alexei
    The action of some coordinative compounds of Cr(III) on Spirulina strain growth and development has been studied. High stimulation action of K2[Cr(NTA)(C2O4)(H2O)]·2H2O and [K2Cr2(SO4)4]·12H2O on Spirulina productivity has been established.
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    STUDIUL UNOR PARAMETRI DE CULTIVARE A MICROALGEI VERZI DUNALIELLA SALINA LA CREŞTEREA PE LICHID CULTURAL REZULTAT DIN PRODUCEREA BIOMASEI DE SPIRULINĂ
    (CEP USM, 2007) Bivol, Cezara; Rudic, Valeriu
    After cultivating blue-green algae Spirulina platensis remains its cultural liquid actually becomes a biotechnological waste. This liquid contains important biologically active substances and might be used as culture medium for other microalgae. An appropriate representative is the green microalgae Dunaliella salina – a valuable source of β-carotene. The medium D. salina optimization has been carried out. The major cultural factors of influence (salinity, light intensity) on Dunaliella salina productivity have been determined.
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    CAPACITATEA ANTIOXIDANTĂ A PREPARATELOR DE FICOCIANINĂ OBŢINUTE ÎN BAZA BIOMASEI DE SPIRULINĂ ÎMBOGĂŢITE CU GERMANIU
    (CEP USM, 2012) Bulimaga, Valentina; Djur, Svetlana; Pisov, Maria; Rudi, Liudmila; Rudic, Valeriu
    The optimal time to harvest spirulina biomass for phycocyanin extraction was established. The phycocyanin yield and purity depend on used extracting solution, recording the maximum values for 1% CaCl2 solution in 10% alcohol. The testing for antioxidant activity of phycocyanin preparations by ABTS+ was carried out for both: preparations obtained from spirulina biomass grown on Zarrouk medium, as well as those obtained from biomass cultivated on medium enriched with germanium. The antioxidant activity of containing germanium phycocyanin preparations was the highest.
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    STUDIUL INFLUENŢEI COMPUŞILOR COORDINATIVI AI Cu(II) ASUPRA PRODUCTIVITĂŢII CIANOBACTERIEI SPIRULINA PLATENSIS
    (CEP USM, 2009) Rudic, Valeriu; Batîr, Ludmila; Gulea, Aurelian; Ţapcov, Victor
    The productivity of cyanobacteria Spirulina platensisat the cultivation in presence of coordinative compound of Cu(II) havs been determined. The spirulina productivity depends on coordination compounds nature and concentrations. Coordinative compounds: [Cu(L1-H)H2O(NO3)], CuL32(NO3)2 and CuL(NO3)2 had the most favorable effect for biomass accumulation