The article deals with the aspects related to lyophilization of streptomycetes strains, preserved in the National
Collection of Nonpathogenic Microorganisms (NCNM). Was determined that lyophilization do not significantly modify
the antimicrobial activity of streptomycetes. Maximum viability of strains of genus Streptomyces (83,2-90,2%) is ensured
after lyophilization at initial titer by 9-11 log10UFC ml-1 in protective medium (gelatin 2,5% + glucose 7,5%) by rehydration
with distillate water