The article presents new data on distribution in the spontaneous flora of the Republic of Moldova and the study results on Asperula species: Asperula rumelica Boiss. and Asperula tenella Heuff. ex Degen. – two rare species (Rubiaceae Juss. family) proposed for inclusion in the national Ecological legislation and to the Red Book of the Republic of Moldova, 4th edition. The following data for these taxa are indicated: Latin, Romanian and Russian names, synonymy, category and criteria of rarity, local distribution, habitat, limiting factors, biological and ecological characteristics, status and conservation measures protection in the republic.
