The paper presents the synthesis of the ligand 5-nitrofuran-2-carbaldehyde N(4)-allyl-3-thiosemicarbazone (HL) and
eight coordination compounds of copper(II) and nickel(II) with this ligand. The structure of thiosemicarbazone HL was
studied using 1
H and 13С NMR spectroscopy. For the synthesized compounds their antimicrobial and antifungal activity
was studied on a series of standard strains. For HL and Cu(HL)2(NO3)2 the antitumor activity towards human leukemia
HL-60 cells was estimated. It was established that coordination compounds manifest better activity than free ligand.
