Browsing by Author "Babileva, Anastasia"

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    THE IMPACT OF FOOD RATIONS ON THE INTERMEDIATE METABOLISM OF AMINO ACIDS IN INDIVIDUALS WITH HYPERSTHENIC TYPE OF CONSTITUTION
    (CEP USM, 2024) Babileva, Anastasia
    The advancement of personalized nutrition systems holds significance in the future of personalized medicine. The research paper outlines the fundamental principles of sanogenic nutrition based on the hypersthenic constitution type, which serves as a criterion for individualization. When creating and computing the caloric makeup of diets for hypersthenics, special emphasis is placed on the observation that individuals with this body type have a propensity to gain weight effortlessly and encounter difficulties in shedding excess body mass. Considering the principle of food differentiation and metabolic idiosyncrasies, the hypersthenic diet should primarily comprise of nourishments that promote a decreased metabolism, rather than ones that hinder it. This entails including foods abundant in protein and limited in carbohydrates and fats. Upon analyzing the obtained findings, it can be deduced that the food ration with a protein content ranging from 20-22% is more favorable for the nitrogen metabolism process in rats of this type of constitution.
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    INFLUENŢA RAŢIILOR ALIMENTARE ÎN RAPORT CU TIPUL HIPERSTENIC DE CONSTITUŢIE ASUPRA ACTIVITĂŢII ENZIMELOR PROTEOLITICE ŞI AMILOLITICE
    (CEP USM, 2024) Babileva, Anastasia; Strutinschi, Tudor; Mereuţă, Ion
    Viitoarea medicină personalizată se va concentra pe dezvoltarea sistemelor de nutriție personalizate. Pentru individualizare, lucrarea prezintă principiile fundamentale ale nutriției sanogenice în funcție de tipul de constituție. Pentru constituția de tip hiperstenic, au fost create patru variante de rații alimentare cu diferit procentaj caloric. În cadrul cercetărilor efectuate, au fost identificate caracteristicile activității enzimelor amilolitice, proteolitice ale intestinului subțire, ale pancreasului și ale peptidazelor stomacului la animalele cu constituție hiperstenică, atunci când sunt influențați factorii nutritivi. Datele colectate au arătat că la animalele cu un nivel scăzut de stresoreactivitate, activitatea enzimelor digestive depinde de macronutrienții compoziției rației alimentare și de structura calorică a rației alimentare. Totodată s-a remarcat că, în comparație cu reprezentanții altor tipuri de constituție, sistemele enzimatice ale organelor digestive sunt mai rezistente la modificările structurii calorice a rației alimentare la reprezentanții tipului hiperstenic de constituție.
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    INFLUENȚA STRUCTURII CALORICE A RAȚIILOR ASUPRA METABOLISMULUI INTERMEDIAR AL AMINOACIZILOR LIBERI ESENȚIALI LA TIPUL ASTENIC AL CONSTITUȚEI
    (CEP USM, 2024) Babileva, Anastasia; Carauş, Vladimir
    The advancement of personalized nutrition systems holds significance in the future of personalized medicine. The research paper outlines the fundamental principles of sanogenic nutrition based on the asthenic constitution type, which serves as a criterion for individualization. Individuals with an asthenic constitution type are primarily characterized by a heightened level of metabolic processes, which influences their dietary requirements. To ensure sustainable and healthy metabolism and morphophysiological functioning, the nutrition of asthenic individuals should focus on maintaining a high metabolic rate. The diet for asthenic individuals primarily consists of products that support an elevated metabolism without further stimulation (as it is already high in asthenics). These products include energy-rich foods like carbohydrates and lipids, while proteins are consumed in minimal quantities.
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    STUDIEREA INFLUENŢEI NUTRIENŢILOR GENERATORI DE ENERGIE PENTRU TIPUL NORMOSTENIC AL CONSTITUŢIEI ASUPRA METABOLISMULUI INTERMEDIAR AL AMINOACIZILOR
    (CEP USM, 2024) Babileva, Anastasia
    The development of individualized nutrition systems is relevant to the personalized medici ne of the future. The paper presents the fundamental principles of sanogenic nutrition according to the type of constitution (the normosthenic type of constitution), which was used as a criterion for individualization. In order to perform the tasks of the research stage, 4 variants of rations with different calorific value for the normosthenic type of constitution were elaborated. In order to interpret the biological value of the rations used more widely, the entire spectrum of amino acids has been studied. For the assessment of general physiological status, free amino acid pool in rat blood serum and erythrocytes was evaluated. In normosthenic rats, maintained with rations with 16-20% protein, the antioxidant potential of the body is within stable limits, which reflects the limits of the compensatory possibilities of the organism of normosthenic rats. The optimal coefficient of distribution of amino nitrogen between erythrocytes and serum in the blood is also 1.8 and is closer to the optimal one.