DFT EVIDENCE OF MUTUAL ANTIOXIDANT ACTION OF CAFFEIC ACID AND GLUTATHIONE IN THEIR REACTIONS WITH ABTS+•
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Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
CEP USM
Abstract
It was shown that unlike other food acids, the caffeic one exhibits a signifcant synergistic
effect with glutathione in the aBTs+• assay. It was found that the main stages of mechanism
of this synergistic interaction is determined by the presence of the 3-OH and 4-OH hydroxyl
groups in the structure of caffeic acid and the greater stability of its anion which contains the
deprotonated 4-OH hydroxyl group compared with the anion with its deprotonated carboxyl
group.
Description
GORBACHEV, Mikhail, GORINCHOY, Natalia, BĂLAN, Iolanta. DFT evidence of mutual antioxidant action of caffeic acid and glutathione in their reactions with ABTS+•. In: Integrare prin cercetare și inovare: conferința științifică națională cu participare internațională. Ştiinţe ale naturii și exacte, 9-10 noiembrie 2023. CEP USM, 2024, pp. 509-514. ISBN 978-9975-62-690-3.
Keywords
synergistic effect, caffeic acid and glutathion, ABTS+• test, DFT study
Citation
GORBACHEV, Mikhail, GORINCHOY, Natalia, BĂLAN, Iolanta. DFT evidence of mutual antioxidant action of caffeic acid and glutathione in their reactions with ABTS+•. In: Integrare prin cercetare și inovare: conferința științifică națională cu participare internațională. Ştiinţe ale naturii și exacte, 9-10 noiembrie 2023. CEP USM, 2024, pp. 509-514. ISBN 978-9975-62-690-3.