КАТАЛИТИЧЕСКИЙ ХАРАКТЕР ЭВТЕКТИЧЕСКИХ СМЕСЕЙ В СИНТЕЗЕ ДИГИДРОПИРИМИДИНОВ

Abstract

One of the current trends in modern science is “green chemistry” - this is a scientific direction in chemistry, which includes any improvement in chemical processes that has a positive effect on the environment. From the point of view of “green chemistry”, which is as waste-free and environmentally friendly as possible, it is of interest to obtain ionic liquids containing various active groups, such as cyanoethyl, carboxyl, etc., and on their basis to obtain eutectic mixtures with thiourea, urea and study their catalytic properties in the synthesis of various substituted dihydropyrimidines. It is interesting that both ES and their components separately consist of pharmacophore structures and are of pharmaceutical and biological interest. Moreover, each element of the ES, as well as the ES as a whole, fully meets the modern requirements of biodegradability, bioavailability and the interests of the world ecology.