Browsing by Author "Kacso, Irina"

Filter results by typing the first few letters
Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Spectrophotometric studies of sanguinarine- β - cyclodextrin complex formation [Articol]
    (Academia de Știinițe a Moldovei, 2008) Boldescu, Veaceslav; Kacso, Irina; Bratu, Ioan; Duca, Gheorghe
    The main aim of this study was to investigate the infl uence of pH and the presence of hydrophilic polymer polyvinylpyrrolidone on the formation of sanguinarine-β-cyclodextrin (SANG-β-CD) inclusion complex. Spectrophotometric studies of the SANG-β-CD systems in the presence and without 0.1 % PVP at the pH 5.0 did not show any evidence of the complex formation. However, the same systems showed several obvious evidences at the pH 8.0: the hyperchromic and the hypochromic effects and the presence of the isosbestic point in the region of 200 – 210 nm. The association constants calculated by three linear methods: Benesi-Hildebrand, Scott and Scatchard, were two times higher for the systems with addition of 0.1% PVP than for the systems without it.