Browsing by Author "Blaja, Svetlana"
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Item COMPOZIȚIA CHIMICĂ A ULEIULUI VOLATIL DE NARCIS (NARCISSUS POETICUS L.) LOCAL(CEP USM, 2024) Ciocârlan, Alexandru; Arîcu, Aculina; Lungu, Lidia; Blaja, Svetlana; Dragalin, Ion; Popescu, VioletaSpecies of the Narcissus genus are important sources of biologically active compounds frequently used in various fields. Concrete, absolute, extracts and essential oil obtained from Narcissus poeticus L. plants, due to their specific chemical composition, are unique ingredients for the perfumery industry in the development of luxury products and medicine. The chemical composition of the concrete obtained from local narcissus plants has been described previously. In this paper, the data regarding the extraction of absolute from concrete and its chemical composition are reported. As result of the GC-MS analysis, 16 constituents belonging to various classes of natural compounds were identified.Item COMPUȘI NORLABDANICI BIOLOGIC ACTIVI. STUDIU COMPARATIV: TESTĂRILE IN VITRO VERSUS TESTUL DE ANDOCARE MOLECULARĂ(CEP USM, 2024) Lungu, Lidia; Ciocârlan, Alexandru; Blaja, Svetlana; Vornicu, Nicoleta; Bolocan, Natalia; Arîcu, AculinaThe results of this paper describe the comparative study of in vitro assays compared to the molecular docking assay of biologically active oxygenated norlabdane compounds and terpeneheterocyclic hybrid compounds, obtained from (-)-sclareol, (+)-larixol and larixyl acetate. The in vitro antimicrobial activity of the obtained compounds was tested on fve strains of fungi and two species of Gram-positive and Gram-negative bacteria. The results of the presented computational simulations correlate very well with the experimental outcome and highlight the three most active norlabdane compounds with heterocyclic fragment.Item EFFECT OF SOME ESSENTIAL OILS ON Acanthoscelides obtectus SAY (COLEOPTERA: BRUCHIDAE) AND Tetranychus urticae KOCH, (ACARI: TETRANYCHIDAE) ADULTS(CEP USM, 2024-10-07) Muntyan, Elena; Ciocarlan, Alexandru; Kulcitki, Veaceslav; Batco, Mihail; Aricu, Aculina; Lungu, Lidia; Blaja, Svetlana; Popescu, VioletaIn search of new and safe pesticides, the toxicity of volatile oils obtained from three plant species against Acanthoscelides obtectus and Tetranychus urticae adults was studied. The essential oils of peppermint (Mentha piperita L), rosemary (Rosmarinus officinalis L) and coriander (Coriandrum sativum L) showed higher toxicity on mites than on weevils. The peppermint and rosemary essential oils demonstrated efficacy against A. obtectus in both fumigant and acute contact toxicity tests. The peppermint and coriander essential oils had the most pronounced fumigant toxicity to mites, with LT50 of 2.5 and 3.7 h, respectively, at 5 µg/cm³ air and are the most promising sources of natural substances with acaricidal properties.Item Effect of some essential oils on Acanthoscelides obtectus Say (coleoptera: bruchidae) and Tetranychus urticae koch, (acari: tetranychidae) adults(CEP USM, 2024) Muntyan, Elena; Ciocarlan, Alexandru; Kulcitki, Veaceslav; Batco, Mihail; Aricu, Aculina; Lungu, Lidia; Blaja, Svetlana; Popescu, VioletaIn search of new and safe pesticides, the toxicity of volatile oils obtained from three plant species against Acanthoscelides obtectus and Tetranychus urticae adults was studied. The essential oils of peppermint (Mentha piperita L), rosemary (Rosmarinus officinalis L) and coriander (Coriandrum sativum L) showed higher toxicity on mites than on weevils. The peppermint and rosemary essential oils demonstrated efficacy against A. obtectus in both fumigant and acute contact toxicity tests. The peppermint and coriander essential oils had the most pronounced fumigant toxicity to mites, with LT50 of 2.5 and 3.7 h, respectively, at 5 μg/cm³ air and are the most promising sources of natural substances with acaricidal properties.Item PRELIMINARY PHYTOCHEMICAL ANALYSIS OF CRUD EXTRACT FROM TANACETUM CORYMBOSUM (L.) SHI. BIP.(CEP USM, 2022-09-29) Ciocârlan, Alexandru; Aricu, Aculina; Lungu, Lidia; Blaja, Svetlana; Popescu, Violeta; Zinicovscaia, Inga; Carrupt, ValentinItem SINTEZA DIRIJATĂ ŞI STUDIUL ACTIVITĂŢII ANTIMICROBIENE A UNOR COMPUŞI NORLABDANICI POLIFUNCŢIONALIZAŢI(2022) Blaja, SvetlanaElaborarea metodelor eficiente de sinteza dirijată a compușilor norlabdanici optic activi noi cu fragmente tiosemicarbazonice, 1,3-tiazolice, 1,3,4-tiadiazolice și benzotiazolice, în baza diterpenoidei labdanice naturale sclareol; elucidarea mecanismelor posibile ale reacțiilor de sinteză a compușilor polifuncționalizați care sunt înzestrați cu activitate biologică promițătoare.Item SINTEZA DIRIJATĂ ŞI STUDIUL ACTIVITĂŢII ANTIMICROBIENE A UNOR COMPUŞI NORLABDANICI POLIFUNCŢIONALIZAŢI(2022) Blaja, Svetlana; Arîcu, AculinaScopul și obiectivele lucrării constau în elaborarea metodelor eficiente de sinteză dirijată a compușilor norlabdanici optic activi noi cu fragmente tiosemicarbazonice, 1,3-tiazolice, 1,3,4-tiadiazolice și benzotiazolice, în baza diterpenoidei labdanice naturale sclareol; elucidarea mecanismelor posibile ale reacțiilor de sinteză a compușilor polifuncționalizați care sunt înzestrați cu activitate biologică promițătoare.Item SYNTHESIS OF NEW POTENTIAL ACTIVE HOMODRIMANE SESQUITERPENOIDS WITH BENZIMIDAZOLE FRAGMENT(CEP USM, 2022-09-29) Lungu, Lidia; Blaja, Svetlana; Cucicova, Carelia; Ciocârlan, Alexandru; Aricu, Aculina