Browsing by Author "Звягинцева, Марина"

Filter results by typing the first few letters
Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    ПОЛУСЕНИЕ ПРОИЗВОДНЫХ КЛАССА ПИРАЗОЛА ГЕТЕРОЦИКЛИЗАЦИИ 1,2,4-ТРИАЗОЛИЛЭТАНОНОВ
    (CEP USM, 2024) Звягинцева, Марина; Сукман, Наталья; Макаев, Флюр
    In this work the peculiarities of the heterocyclization reaction of vinyltriazoles with the participation of hydrazine hydrate in ethanol and acetic acid are considered. Within the framework of this work it was found that the nature of the formed reaction products of the interaction of vinyltriazoles with hydrazine hydrate depends on the nature of the solvent. In boiling ethanol, 4,5-dihydro-1H-pyrazolinfunctionalized 1H-1,2,4-triazole is formed. Under acetic acid conditions, along with the formation of a pair of diastereomeric substances 4,5-dihydro-1H-pyrazoline series diastereomeric substances undergoing acylation, the formation of triazolium salt of acetic acid undergoes decomposition with cleavage of 1H-1,2,4-triazole fragment and formation of 3,5-disubstituted pyrazole. The structure of the obtained compounds was confirmed by spectral data and elemental analysis