Pahonțu, ElenaFala, ValeriuGulea, AurelianPoirier, DonaldȚapcov, VictorRoșu, Tudor2023-10-262023-10-262013PAHONȚU, Elena, FALA, Valeriu, GULEA, Aurelian, POIRIER, Donald, ȚAPCOV, Victor , ROȘU, Tudor. Synthesis and characterization of some new Cu(II), Ni(II) and Zn(II) complexes with salicylidene thiosemicarbazones: Antibacterial, antifungal and in vitro antileukemia activity. În: Molecules, 2013, vol. 18, pp. 8812-8836. ISSN 1420-30491420-3049https://msuir.usm.md/handle/123456789/11477https://doi.org/10.3390/molecules18088812Thirty two new Cu(II), Ni(II) and Zn(II) complexes (1-32) with salicylidene thiosemicarbazones (H2L1-H2L10) were synthesized. Salicylidene thiosemicarbazones, of general formula (X)N-NH-C(S)-NH(Y), were prepared through the condensation reaction of 2-hydroxybenzaldehyde and its derivatives (X) with thiosemicarbazide or 4-phenylthiosemicarbazide (Y = H, C6H5). The characterization of the new formed compounds was done by 1H-NMR, 13C-NMR, IR spectroscopy, elemental analysis, magnetochemical, thermoanalytical and molar conductance measurements. In addition, the structure of the complex 5 has been determined by X-ray diffraction method. All ligands and metal complexes were tested as inhibitors of human leukemia (HL-60) cells growth and antibacterial and antifungal activities.encoppernickelzinc complexesthiosemicarbazonesantimicrobial activityantileukemiaArticle