Gorbachev, MikhailGorinchoy, NataliaBălan, Iolanta2024-03-262024-03-262024GORBACHEV, Mikhail, GORINCHOY, Natalia, BĂLAN, Iolanta. DFT evidence of mutual antioxidant action of caffeic acid and glutathione in their reactions with ABTS+•. In: Integrare prin cercetare și inovare: conferința științifică națională cu participare internațională. Ştiinţe ale naturii și exacte, 9-10 noiembrie 2023. CEP USM, 2024, pp. 509-514. ISBN 978-9975-62-690-3.978-9975-62-690-3https://msuir.usm.md/handle/123456789/14604GORBACHEV, Mikhail, GORINCHOY, Natalia, BĂLAN, Iolanta. DFT evidence of mutual antioxidant action of caffeic acid and glutathione in their reactions with ABTS+•. In: Integrare prin cercetare și inovare: conferința științifică națională cu participare internațională. Ştiinţe ale naturii și exacte, 9-10 noiembrie 2023. CEP USM, 2024, pp. 509-514. ISBN 978-9975-62-690-3.It was shown that unlike other food acids, the caffeic one exhibits a signifcant synergistic effect with glutathione in the aBTs+• assay. It was found that the main stages of mechanism of this synergistic interaction is determined by the presence of the 3-OH and 4-OH hydroxyl groups in the structure of caffeic acid and the greater stability of its anion which contains the deprotonated 4-OH hydroxyl group compared with the anion with its deprotonated carboxyl group.ensynergistic effectcaffeic acid and glutathionABTS+• testDFT studyArticle