Gulea, AurelianGudumac, ValentinGarbuz, Olga2021-01-202021-01-202021GARBUZ, Olga. New inorganic and organic molecular inhibitors of cancer cells proliferation, the mechanisms of action: teză de doctor în științe biologice. Ch.: 2021. 172 p..https://msuir.usm.md/handle/123456789/3634Doctoral thesis in biological sciences - Scientific supervisor: academician, habilitated doctor of chemical sciences, univ. professor, Emeritus Person of the Republic of Moldova, Aurelian GULEA: Scientific consultant: habilitated doctor of medical science, univ. professor, Emeritus Person of the Republic of Moldova, Valentin Gudumac.The aim of the thesis: elucidation of the effect of the new molecular inhibitors based on organic and complex compounds on the proliferation of human cancer cell lines in comparison with such anticancer drugs as doxorubicin and cis-dichlorodiammineplatinum; determination of the inhibitors action mechanism.Scopul lucrări: elucidarea efectului noilor inhibitori moleculari pe bază de compuși organici și complecși asupra proliferării liniilor celulare ale cancerului uman în comparație cu medicamentele anticanceroase doxorubicina și cis-diclorodiamminplatinum; determinarea mecanismului de acțiune a inhibitorilor.Цель: выявление влияния новых молекулярных ингибиторов на основе органических и комплексных соединений на пролиферацию линий раковых клеток человека в сравнении с используемыми противораковыми препаратами доксорубицином и цис-дихлородиамминплатиной; определение механизма действия ингибиторов.enanticancer compoundhemolysishuman cancer cell lineantioxidant activitycompuși anticancerhemolizăcelule canceroase umaneactivitate antioxidantăпротивораковое веществораковые клетки человекаантиоксидантная активностьгемолизThesis