Lupaşcu, LucianGavzer, SvetlanaCristea, NicolaeLupaşcu, GalinaStîngaci, EugeniaZveaghinţeva, MarinaSucman, NataliaMacaev, Fliur2025-03-192024LUPAŞCU, Lucian; Svetlana GAVZER; Nicolae CRISTEA; Galina LUPAŞCU; Eugenia STÎNGACI; Marina ZVEAGHINŢEVA; Natalia SUCMAN și Fliur MACAEV. Activitatea antifungică a noilor derivați vinil-triazolici către Fusarium culmorum (W.G. Sm.) sacc. In: Integrare prin cercetare și inovare: conferință științifică națională cu participare internațională. Științe exacte și ale naturii, Chișinău, 7-8 noiembrie, 2024. Chișinău: CEP USM, 2024, pp. 622-629. ISBN 978-9975-62-808-2 (PDF). Disponibil: https://doi.org/10.59295/spd2024n.86978-9975-62-808-2 (PDF)https://doi.org/10.59295/spd2024n.86https://msuir.usm.md/handle/123456789/17137Objectives: identification of new compounds with antifungal activity for the phytopathogenic fungus Fusarium culmorum. Methods: the isolation of F. culmorum strains was carried out in aseptic conditions on PDA (Potatoes Dextrose Agar) medium, with the subsequent identification of the species based on macro- and microscopic characteristics. Vinyl-triazole derivatives (D.V.T): EPS-165, MZ-115, MZ-118, EPS-23 were supplemented to the nutrient medium PDA in concentrations of 0,02; 0,01; 0,005; 0,0025; 0,00125%, sterilized by autoclaving. To assess the inhibitory effect of the studied preparations, the method of recording the diameter of the growing colonies was used. Results: the inhibitory effect of the studied preparations was specific depending on the concentration and the strain of the fungus investigated. The preparation MZ-118 offers wider opportunities for use in plant protection measures against the fungus F. culmorum. The factorial analysis demonstrated that in the system F. culmorum x D.V.T. x concentration, the main source of variation in fungal growth is D.V.T concentration. (50.2 ... 64.4%), followed by the isolate factor (24.7 ... 38.9%), which denotes the differential resistance of F. culmorum isolates to the action of the compounds under study.roactivityconcentrationsvinyl-triazole derivativesfungiactivitateconcentrațiiderivați vinil-triazoliciACTIVITATEA ANTIFUNGICĂ A NOILOR DERIVAȚI VINIL- TRIAZOLICI CĂTRE FUSARIUM CULMORUM (W.G. SM.) SACC IN VITROANTIFUNGAL ACTIVITY OF NEW VINYL-TRIAZOLE DERIVATIVES AGAINST FUSARIUM CULMORUM (W.G. SM.) SACC IN VITROArticlehttps://doi.org/10.59295/spd2024n.86