Popușoi, AnaBarba, NicanorGulea, AurelianRoy, JennyPoirier, Donald2023-10-192023-10-192014POPUȘOI, Ana, GULEA, Aurelian, BARBA, Nicanor, ROY, Jenny, POIRIER, Donald. Substituted 1,3-phenyl (pyridyl) propenones and derivatives with thiosemicarbazidic groups. Structrure – (hl-60) antileukemia activity relationship. În: Chemistry Journal of Moldova, 2014, nr. 2(9), pp. 67-73. ISSN 1857-17271857-1727https://msuir.usm.md/handle/123456789/11395http://10.19261/cjm.2014.09(2).103-(4-(Dimethylamino)phenyl-1-(4-isothiocyanatophenyl)prop-2-en-1-one was obtained from the corresponding N,N-dimethylthyoureas by elimination of dimethylamine at heating with gaseous hydrogen chloride in chloroform and 1-(4-isothiocyanatophenyl)-3-(pyridin-2-il)prop-2-en-1-one by treating 1,1-dimethyl-3-(4-(3-(pyridin-2-il)-acryloyl)-phenyl)thyourea with acetic anhydride. For all obtained compounds in the course of reaction the antileukemia activity was investigated.enchalconesisothiocyanatopropenonesthioureasantileukemia activityArticle