Chumakov, Yu. M.Graur, V. O.Ulchina, Ya. I.Smaglii, V. A.Gulea, A. P.Garbuz, O. S.Tsapkov, V. I.2023-09-212023-09-212022CHUMAKOV, Y., GRAUR, V., ULCHINA (GRAUR), Y., SMAGLII, V., GULEA, A., GARBUZ, O., TSAPKOV, V. Crystal structures of [N′-(2-oxidobenzylidene)-N-(prop-2-en-1-yl)-carbamohydrazonothioato (2-)](1, 10-phenanthroline) copper and [N′-(2-oxidobenzylidene)-N-(prop-2-en-1-yl)-carbamohydrazonothioato (2-)](2, 2′-bipyridine) copper hemihydrates. In: Journal of Structural Chemistry. 2022, vol. 63, nr. 6, pp. 905-913. ISSN 0022-4766. IF 1.004 DOI: https://doi.org/10.1134/S00224766220600750022-4766https://doi.org/10.1134/S0022476622060075https://msuir.usm.md/handle/123456789/10978The crystal structures and biological properties of [N′-(2-oxidobenzylidene)-N-(prop-2-en-1-yl)-carbamohydrazonothioato(2-)](1,10-phenanthroline)copper hemihydrate [Cu(1,10-Phen)(L)]·0.5H2O (I) and [N′-(2-oxidobenzylidene)-N-(prop-2-en-1-yl)-carbamohydrazonothioato(2-)](2,2′-bipyridine)copper hemihydrate [Cu(2,2′-BPy)(L)]·0.5H2O (II), where Н2L is 2-(2-hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamide, are determined. The asymmetric unit of the unit cell in the crystal structures of I and II contains a copper complex with bidentate amine and a ligand coordinated by the azomethine nitrogen atom, the deprotonated phenolic oxygen atom, and the sulfur atom in the thiol form. The coordination polyhedron of the copper atom in compounds I and II is a distorted tetragonal pyramid. Obtained coordination compounds I and II exhibit antimicrobial and antifungal activities and have minimum inhibitory concentration and bactericidal concentration values in a range of 1.5-500 µg/mL. The study of the antioxidant activity shows that compounds I and II are less active than uncoordinated thiosemicarbazone H2L, but more active than trolox used in medical practice.enArticle